Nmda nr2b antagonists for the treatment of depression

A - Human Necessities – 61 – K

Patent

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A61K 31/453 (2006.01) A61K 31/451 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2357929

The invention provides new methods for treating certain disorders resulting from neurodegeneration and for treating depression which comprise administration of NR2B subunit selective NMDA antagonists. The disorders that can be treating by the invention include hearing loss, vision loss, neurodegeneration caused by epileptic seizures, neurotoxin poisoning, Restless Leg Syndrome, multi-system atrophy, non-vascular headache, and depression.

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