Nmr spectroscopy data recovery method and apparatus

G - Physics – 01 – V

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G01V 3/00 (2006.01) G01R 33/46 (2006.01)

Patent

CA 2442618

NMR spectroscopy data recovery methods and apparatus for improving the quality of an NMR spectrum are disclosed. The NMR spectrum is improved by acquiring more than the half spin-echo data signal(301) and using an iterative numerical method to reconstruct the missing data points of the corresponding full symmetrical spin-echo data signal. The method includes filtering the initial data signal to extract a low-resolution phase term (302). The low-resolution phase term is used to form a phase-constrained initial data signal, which is Fourier-transformed to obtain a reconstructed data signal (303). The reconstructed data signal is modified to include the original spin-echo signal data (304). The formation of the reconstructed spin-echo data signal and subsequent modification is iterated until convergence is obtained. The reconstructed data signal is then Fourier-transformed to form a reconstructed NMR spectrum (305).

L'invention concerne des procédés et des dispositifs pour la récupération de données de spectroscopie RMN, qui permettent d'améliorer la qualité d'un spectre NMR, grâce à l'acquisition de plus de la moitié du signal de données d'écho spin (301) et à l'utilisation d'une technique d'itération numérique visant à reconstruire les points de données manquants du signal symétrique correspondant de données d'écho spin complet. Après le filtrage du signal de données initial qui permet d'extraire un terme de phase à faible résolution (302), on utilise ce terme pour établir un signal de données initial à contrainte de phase, auquel est appliquée une transformation de Fourier fournissant le signal de données reconstruit (303). On modifie ensuite ce signal pour y inclure les données du signal d'écho spin original (304). La version reconstruite et modifiée est alors soumise à une itération jusqu'à la convergence. Enfin, on applique une transformation de Fourier au signal de données reconstruit pour établir un spectre NMR reconstruit (305).

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