No synthase assay particles and method

G - Physics – 01 – N

Patent

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G01N 33/58 (2006.01) C12Q 1/26 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2441985

The invention relates to particles for use in a scintillation proximity assays. In particular, the invention relates to particles for use in a scintillation proximity assay for detecting nitric oxide synthase activity in a sample. The invention also relates to a method of measuring nitric oxide synthase activity in a sample using these particles in a scintillation proximity assay. The invention further relates to methods using these particles to detect the presence of modulators of nitric oxide synthase activity.

L'invention concerne des particules à utiliser dans des dosages de la scintillation par proximité. Plus précisément, l'invention concerne des particules à utiliser dans un dosage de la scintillation par proximité permettant de détecter une activité de l'oxyde nitrique synthétase dans un échantillon. L'invention concerne également un procédé de mesure de l'activité de l'oxyde nitrique synthétase dans un échantillon au moyen de ces particules dans un dosage de la scintillation par proximité. L'invention concerne également des procédés mettant en oeuvre ces particules aux fins de détection de la présence de modulateurs de l'activité de l'oxyde nitrique synthétase.

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