C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01) C12N 5/04 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2427684
The present invention relates to intracellular signaling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides isolated nucleotide sequence encoding Nod2, isolated Nod2 peptides, antibodies that specifically bind Nod2, methods for the detection of Nod2, and methods for screening compounds for the ability to alter Nod2 associated signal transduction.
La présente invention concerne des molécules de signalisation intracellulaire, en particulier, la protéine Nod2 et les acides nucléiques codant pour la protéine Nod2. La présente invention concerne une séquence nucléotidique isolée codant pour Nod2, des peptides Nod2 isolés, des anticorps se liant tout particulièrement à Nod2, des procédés permettant de détecter la Nod2, et des procédés de criblage de composés permettant de modifier la transduction de signal associée à Nod2.
Inohara Naohiro
Nunez Gabriel
Ogura Yasunori
Smart & Biggar
The Regents Of The University Of Michigan
LandOfFree
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