Non-a, non-b hepatitis assay and vaccine

Details Non-a, non-b hepatitis assay and vaccine Non-a, non-b hepatitis assay and vaccine

C - Chemistry, Metallurgy

12

N

167/130, 195/33,

C12N 7/00 (2006.01) A61K 39/29 (2006.01) G01N 33/569 (2006.01) G01N 33/576 (2006.01)

Patent

CA 1261773

NON-A, NON-B HEPATITIS ASSAY AND VACCINE ABSTRACT OF THE INVENTION A newly discovered particle in the urine and serum of non-A, non-B hepatitis patients has been associated with non-A, non-B hepatitis. The particle resembles a togavirus and is 50-60 nm in diameter with a discrete core of about 40 nm in diameter. The virus loses its infectivity for tissue culture upon heating at 25° C in aqueous suspension or by exposure to ether. The particle may be cultured in vitro or recovered from body fluids or tissues to make immunoassays and vaccines. The immunoassays may be em- ployed to detect the particle antigens or antibodies thereto in test samples.

400069

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