Non-a, non-b hepatitis virus genomic cdna and antigen...

Details Non-a, non-b hepatitis virus genomic cdna and antigen... Non-a, non-b hepatitis virus genomic cdna and antigen...

C - Chemistry, Metallurgy

12

N

C12N 15/51 (2006.01) A61K 39/29 (2006.01) C07K 14/18 (2006.01) C12N 1/21 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/576 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2045323

Disclosed is an isolated non-A, non-B hepatitis virus genomic cDNA covering the entire region of the virus gene nucleotide sequence from the 1st to 9416th nucleotides, wherein the coding region is from the 333rd to 9362nd nucleotides, and the 5'- and 3'-noncoding sequences contain 332 nucleotides and 54 nucleotides, respectively. Part of the cDNA and an antigen polypeptide as an expression product thereof are useful as a diagnostic reagent for non-A, non-B hepatitis. The antigen polypeptide is also useful as an active ingredient for a non-A, non-B hepatitis virus vaccine.

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