Non-ad5 adenoviral vectors and methods and uses related thereto

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/861 (2006.01) A61K 35/76 (2006.01)

Patent

CA 2750770

The present invention relates to the field of medicine. Specifically, the invention relates to cancer therapies. More specifically, the present invention relates to oncolytic human adenoviral vectors and cells and pharmaceutical compositions comprising said vectors. The present invention also relates to a use of said vectors in the manufacture of a medicament for treating cancer in a subject and a method of treating cancer in a subject. Furthermore, the present invention relates to a method of producing an adenoviral vector.

La présente invention concerne le domaine de la médecine. La présente invention concerne spécifiquement des thérapies contre le cancer. La présente invention concerne plus spécifiquement des vecteurs adénoviraux oncolytiques humains ainsi que des cellules et des compositions pharmaceutiques comprenant lesdits vecteurs. La présente invention concerne également une utilisation desdits vecteurs dans la fabrication d'un médicament destiné au traitement du cancer chez un sujet et un procédé de traitement du cancer chez un sujet. La présente invention concerne en outre un procédé de production d'un vecteur adénoviral.

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