Non-allergenic protective antigens from molds

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 39/35 (2006.01)

Patent

CA 1182749

TITLE NON-ALLERGENIC PROTECTIVE ANTIGENS FROM MOLDS INVENTORS Hari Mohan Vijay Noel Martin Young I. Leonard Bernstein ABSTRACT OF THE DISCLOSURE Certain isolated fractions, extracted from allergy-causing molds, have been found to be antigenic but non-allergenic, and are able to decrease substantially or prevent the susceptibility to mold aller- gens of allergic individuals. The antigenic non-allergenic fractions contain protein and carbohydrate and have molecular weights which have been found to vary with the mold source. Increased polyvalent protec- tion can be realized by combining fractions from different molds, e.g. Alternaria with Hormodendrum or Helminthosporium. The extracts are administered parenterally, preferably subcutaneously in isotonic saline.

396043

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