Non-antigenic amine derived polymers and polymer conjugates

Details Non-antigenic amine derived polymers and polymer conjugates Non-antigenic amine derived polymers and polymer conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07K 14/805 (2006.01) C07K 17/08 (2006.01) C08F 8/30 (2006.01) C08G 65/32 (2006.01) C08G 65/329 (2006.01) C08G 65/333 (2006.01) C12N 9/96 (2006.01) C12N 11/08 (2006.01)

Patent

CA 2191726

Substantially non-antigenic polymers containing pI and/or pH optimum modulating moieties are disclosed. The polymers are useful as intermediates for synthesis of amine-based polymers and in the formation of activated polymers for conjugation with nucleophiles. Conjugates and methods of preparation and treatment with the conjugates are also disclosed.

Polymères pratiquement non antigéniques contenant des fractions qui modulent le pI et/ou le pH optimal, utiles en tant qu'intermédiaires pour la synthèse de polymères à base d'amines et dans la formation de polymères activés en vue de la conjugaison avec des nucléophiles. Des conjugués et des procédés de préparation et de traitement à l'aide desdits conjugués sont également décrits.

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