Non-aqueous oral-drench compositions containing avermectin...

A - Human Necessities – 61 – K

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Details

A61K 47/44 (2006.01) A61K 9/00 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2202707

The invention is directed to a novel non-aqueous oral-drench composition comprising from 0.01% to 2.0% (w/v) of an avermectin compound; from 30% to 45% (w/w) of an oil, said oil being selected from the group consisting of corn oil, sunflower oil, peanut oil and safflower oil; from 0.01% to 1.0% (w/v) of an oil-soluble antioxidant; and from 50% to 70% (w/w) of a fatty acid ester, said fatty acid ester being selected from the group consisting of caprylic/capric triglyceride, octyl palmitate and propylene glycol dicaprylate/dicaprate. The invention is further directed to methods of using the non-aqueous composition to treat parasitic diseases in mammals.

Nouveau breuvage d'usage vétérinaire non aqueux composé de 0,01 à 2,0 % (p/v) d'avermectine, de 30 à 45 % (p/p) d'une huile sélectionnée parmi le groupe composé des huiles de maïs, de tournesol, d'arachide et de carthame, de 0,01 à 1,0 % (p/v) d'un antioxydant oléosoluble, et de 50 à 70 % (p/p) d'un ester d'acide gras choisi parmi le groupe composé de triglycéride caprylique/caprique, de palmitate d'octyle et de dicaprylate/dicaprate de propylène-glycol. La présente invention fait également état d'une méthode d'utilisation de la composition non aqueuse pour traiter des maladies parasitaires chez les mammifères.

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