Non-competitive internal controls for use in nucleic acid tests

Details Non-competitive internal controls for use in nucleic acid tests Non-competitive internal controls for use in nucleic acid tests

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) C12N 15/29 (2006.01) C12N 15/31 (2006.01)

Patent

CA 2718946

Provided are non-competitive internal controls for use in nucleic acid tests (NATs), which are obtained from the organisms Methanobacterium thermoautrophicum (MET) and Zea mays (Corn). The non-competitive internal controls have utility in DNA and RNA NATs selected from Influenza A, Influenza B, parainfluenza viruses 1 to 4(PIV-1 to PIV-4), respiratory syncytial virus type A (RSV A), RSV B, human metapneumovirus (hMPV), Chlamydia trachomatis (CT), and Neisseria gonorrhea (GC), Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human Immunodeficiency Virus I (HIV-1), and Severe Acute Respiratory Syndrome (SARS).

L'invention concerne des contrôles internes non compétitifs destinés à être utilisés dans des essais d'acide nucléique (NAT) obtenus à partir des organismes Methanobacterium thermoautrophicum (MET) et Zea mays (maïs). Les contrôles internes non compétitifs sont utiles dans les essais d'acide nucléique d'ADN et d'ARN sélectionnés à partir des virus de la grippe A, de la grippe B, des virus parainfluenza 1 à 4 (PIV-1 à PIV-4), du virus syncytial respiratoire de type A (RSV A), du RSV B, du métapneumovirus humain (hMPV), de Chlamydia trachomatis (CT) et de Neisseria gonorrhea (GC), du virus de l'hépatite B (HBV), du virus de l'hépatite C (HCV), du virus de l'immunodéficience humaine I (HIV-1) et du syndrome respiratoire aigu grave (SRAS).

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