Non-fibrogenic, alginate-coated transplants, process of...

Details Non-fibrogenic, alginate-coated transplants, process of... Non-fibrogenic, alginate-coated transplants, process of...

C - Chemistry, Metallurgy

12

N

C12N 11/10 (2006.01) A01N 1/02 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 35/12 (2006.01) A61L 27/20 (2006.01) A61L 27/34 (2006.01) A61L 27/36 (2006.01) A61L 27/38 (2006.01) B01J 2/00 (2006.01) C08B 37/04 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 11/04 (2006.01)

Patent

CA 2135770

2135770 9324077 PCTABS00028 A tissue transplant comprises viable, physiologically active, tissue cells and has a non-fibrogenic coating of a divalent metal alginate. The coating has a sufficiently low permeability and a sufficiently large thickness to protect the tissue cells from host immunological agents after transplantation, and is sufficiently permeable and thin to permit the diffusion of sufficient cell nutrients and cell products through the coating required for cell viability. The tissue cells may be pancreatic islet cells, neural cells, renal cortex cells, vascular endothelial cells, thyroid cells, adrenal cells, thymic cells, ovarian cells, hepatic cells, and the like.

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