Non-human animal model for analysis of the origin and...

Details Non-human animal model for analysis of the origin and... Non-human animal model for analysis of the origin and...

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A01K 67/00 (2006.01) A01K 67/027 (2006.01) C07K 14/495 (2006.01) C12N 15/19 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2462017

The invention relates to a non-human animal model for analysis of the origin and therapy of organ fibrosis. The animal model comprises a double transgenic, non human animal with a capacity for conditional and organ-specific development of a fibrosis phenotype. The invention also relates to a method for the production of a double transgenic non-human animal.

L'invention concerne un modèle animal non humain permettant d'analyser l'origine et le traitement d'une fibrose d'organe. Ce modèle animal comprend un animal non humain doublement transgénique pouvant développer de manière organospécifique et sous conditionnement un phénotype de fibrose. L'invention se rapporte en outre à un procédé de production d'un animal non humain doublement transgénique.

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