A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/29 (2006.01) A01K 67/027 (2006.01) A61K 39/00 (2006.01) A61P 37/02 (2006.01) C07K 14/18 (2006.01) C07K 16/28 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12N 15/861 (2006.01) G01N 33/576 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2412498
This invention provides a model for the induction of immunological tolerance to antigens. The tolerance model of the invention can be used for screening candidate drugs effective in modulating tolerance. The invention also provides the use of such tolerance-modulating drugs as agents for the treatment of chronic illnesses, including chronic viral infections, such as HCV.
L'invention concerne un modèle d'induction de tolérance immunologique à des antigènes. Ce modèle de tolérance peut être utilisé dans le criblage de médicaments candidats efficaces dans la modulation de la tolérance. L'invention concerne aussi l'utilisation de tels médicaments, modulant la tolérance, en tant qu'agents de traitement de maladies chroniques, y compris d'infections virales chroniques telles que l'hépatite C chronique.
Borden Ladner Gervais Llp
Chiron Corporation
Novartis Vaccines And Diagnostics Inc.
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