C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) C12N 15/869 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2496620
The present invention relates to animal viruses such as animal herpesviruses as a vector for diagnostic, therapeutic and prophylactic delivery of foreign genes and nucleic acids to animals, human or primary cells derived thereof, respectively. By using said viruses, the prevention and treatment of infectious, autoimmune and tumor diseases as well as allergies and genetic disorders can be treated. The present invention relates further to procedures to efficiently transduce primary human cells with recombinant animal viruses in vitro and in vivo. The invention further relates to a kit useful (i) for diagnosis and monitoring of innate and adoptive immune responses as well as (ii) for gene therapy and (iii) immunization purposes.
L'invention concerne des virus d'animaux tels que des virus de l'herpès utilisés en tant que vecteur dans le diagnostic, le traitement et l'administration prophylactique de gènes étrangers et d'acides nucléiques à des animaux, respectivement des cellules humaines ou primaires dérivées de ceux-ci. En utilisant ces virus, il est possible de prévenir et de traiter des maladies infectieuses, auto-immunes et tumorales ainsi que de traiter les allergies et les troubles génétiques. Cette invention concerne également des procédures destinées à transduire de façon efficace des cellules humaines primaires avec des virus d'animaux recombinant <i>in vitro</i> et <i>in vivo</i>. L'invention concerne enfin un nécessaire utile en vue (i) de diagnostiquer et de réguler des réponses immunitaires innées et adoptives ainsi que (ii) de traiter des gènes et (iii) à des fins d'immunisation.
Beer Martin
Osterrieder Nikolaus
Rudolph Jens
Trapp Sascha
Wagner Ralf
Geneart Ag
Geneart Gmbh
Gowling Lafleur Henderson Llp
LandOfFree
Non-human herpesviruses as vectors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Non-human herpesviruses as vectors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-human herpesviruses as vectors will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1777082