Non-human mammal model comprising heterologous nucleated...

Details Non-human mammal model comprising heterologous nucleated... Non-human mammal model comprising heterologous nucleated...

A - Human Necessities

01

K

A01K 67/027 (2006.01) A61K 49/00 (2006.01) G01N 33/50 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2552913

The invention relates to a method of making a non-human mammal model comprising: a. implanting, into an immunocompromised non-human mammal host, heterologous nucleated cells previously bound to a biocompatible support, b. controlling non-adaptive defences of the non-human mammal host, c. recovering a non-human mammal model harbouring settled heterologous nucleated cells capable of maintaining, differentiating and growing. The invention also relates to a non-human mammal model which is an immunocompromised non-human mammal host implanted with a support comprising heterologous nucleated cells settled thereon, and which non-adaptive defences are controlled to enable the heterologous nucleated cells of said implanted support to maintain, differentiate and grow.

Cette invention concerne un procédé permettant de créer un modèle mammifère non humain, lequel procédé consiste: a) à implanter dans un hôte mammifère non humain immunodéprimé, des cellules nucléées hétérologues préalablement liées à un support biocompatible ; b) à réguler les défenses non adaptatives de l'hôte mammifère non humain ; c) à obtenir un modèle mammifère non humain comprenant des cellules nucléées hétérologues fixées capables de se maintenir, de se différencier et de croître. La présente invention concerne également un modèle mammifère non humain qui est un hôte mammifère non humain immunodéprimé dans lequel on a implanté un support sur lequel sont fixées des cellules nucléées hétérologues et dont les défenses non adaptatives sont commandées de manière à permettre aux cellules nucléées hétérologues dudit support de se maintenir, de se différencier et de croître.

Affiliated with

Also associated with

Rating

Non-human mammal model comprising heterologous nucleated... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Non-human mammal model comprising heterologous nucleated..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-human mammal model comprising heterologous nucleated... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1530603