Non-human transgenic animals for the study of...

A - Human Necessities – 01 – K

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A01K 67/00 (2006.01) A01K 67/027 (2006.01) C07K 16/00 (2006.01) C07K 16/22 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2388341

Non-human transgenic animals as model study for human pathologies, being transgenic for an antibody are disclosed, in particular non-human transgenic animals for anti-NGF (Nerve Growth Factor) antibody able to mimic different pathologies, as neurodegenerative syndromes, to be used as a model to study said pathologies and provide therapies therefor.

L'invention porte sur des animaux transgéniques utilisés dans l'étude de modèles sur des pathologies humaines, ces animaux étant transgéniques pour un anticorps. L'invention porte notamment sur des animaux transgéniques pour un anticorps anti-facteur de croissance neuronal capable d'imiter des pathologies différentes, telles que des syndromes neurodégénératifs, destinées à être utilisées comme modèles pour les étudier et pouvoir y apporter des thérapies.

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