Non-hydrated gabapentin polymorph, a process for the...

C - Chemistry – Metallurgy – 07 – C

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C07C 229/28 (2006.01) C07C 211/35 (2006.01) C07C 227/42 (2006.01)

Patent

CA 2333408

The non-hydrated gabapentine polymorph is obtained by desiccating by atomization or turbodrying an aqueous solution of gabapentine; the invention also relates to its use in order to obtain gabapentine appropriate for pharmaceutical use; disclosed is a method which comprises subjecting the polymorph to a crystallization process in solvents.

L'invention concerne un polymorphe de gabapentine non hydratée que l'on obtient en desséchant par atomisation ou turbo-séchage une dissolution aqueuse de gabapentine et son utilisation pour obtenir de la gabapentine à usage pharmaceutique. L'invention concerne en outre un procédé consistant à soumettre le polymorphe à un processus de cristallisation dans des solvants.

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