Non-infectious hiv-1 particles and uses therefor

Details Non-infectious hiv-1 particles and uses therefor Non-infectious hiv-1 particles and uses therefor

C - Chemistry, Metallurgy

12

N

C12N 15/49 (2006.01) A61K 39/21 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) C12N 15/85 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2067778

2067778 9105860 PCTABS00005 HIV-1 mutant constructs which include a mutation in a nucleotide sequence which is present in wild-type HIV-1, in which it is critical in packaging HIV-1, as well as HIV-1 mutant expression products and HIV mutant viral particles, which are non-infectious. Vaccines which are HIV-1 mutant constructs or HIV-1 mutant expression products, as well as a method if immunizing an individual, comprising administering the vaccine in an appropriate amount.

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