Non-invasive cardiac output and pulmonary function...

A - Human Necessities – 61 – B

Patent

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A61B 5/00 (2006.01) A61B 5/029 (2006.01) A61B 5/083 (2006.01)

Patent

CA 2358446

A cardiac output monitoring system (10) includes a respiratory flowmeter (14) and a gas analyzer (20, 22) capable of determining cardiac output on a breath- by-breath basis by non-invasively measuring properties of respiratory gasses and applying the Fick principle. The gas analyzer has the capability to simultaneously quantify multiple gas concentrations, including inhaled and end- tidal concentrations of any constituent of respiratory gas mixtures of a known number of possible constituents, in real time on a breath-by-breath basis, by measuring independent properties of the mixture. The respiratory flowmeter determines the volumetric and mass flow rates of any gas/gasses as calculated from the product of measured total respiratory flow and the measured volumetric concentration in real time on a breath-by-breath basis. From these measurements, cardiac output can be determined on a breath-by-breath basis by applying appropriate numerical algorithms based on the Fick principal, including corrections for physiological conditions such as shunts and deadspace.

L'invention concerne un système de contrôle (10) du débit cardiaque, qui comprend un débitmètre respiratoire (14) et un analyseur de gaz (20, 22) pouvant déterminer un débit cardiaque par l'oxygène, au moyen d'une technique non invasive de mesure des propriétés de gaz respiratoires, et par application du principe de Fick. L'analyseur de gaz peut mesurer simultanément de nombreuses concentrations de gaz, notamment des concentrations d'inhalation et de fin d'expiration d'un quelconque constituant de mélanges de gaz respiratoires parmi un nombre connu de constituants possibles. Le débitmètre respiratoire détermine les débits volumétrique et massique d'un ou plusieurs gaz calculés à partir du produit du débit respiratoire total et de la concentration volumétrique mesurée par l'oxygène en temps réel. A partir de ces mesures, le débit cardiaque peut être déterminé par l'oxygène, par application d'algorithmes numériques appropriés fondés sur le principe de Fick, y compris des paramètres de correction d'états physiologiques, tels que les chocs pulmonaires ou l'espace mort.

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