Non-invasive method and apparatus for determining a...

A - Human Necessities – 61 – B

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A61B 5/00 (2006.01) A61B 5/01 (2006.01) A61B 5/02 (2006.01) A61B 5/04 (2006.01) A61B 5/0402 (2006.01) A61B 5/0456 (2006.01) A61B 5/05 (2006.01) A61B 5/145 (2006.01) A61B 6/00 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2555807

The present invention relates to an apparatus and method for the non-invasive analysis of physiological attributes, such as heart rate, blood pressure, cardiac output, respiratory response, body composition, and blood chemistry analytes including glucose, lactate, hemoglobin, and oxygen saturation. Using a combination of multi-functioning disparate sensors, such as optical and electrical, improvements are made over existing physiological measurement devices and techniques. The special configuration of one or more multi- functional sensors is used to non-invasively measure multi-wavelength optical plus one or more of ECG, Bio-impedance, and RF-impedance spectroscopic data. This information is used to develop self-consistent, non-linear algorithm in order to derive the physiological attributes while compensating for various forms of interfering effects including motion artifacts, sensor attachment variability, device component variability, subject physical and physiology variability, and various interfering physiological attributes.

Cette invention concerne un appareil et un procédé permettant d'effectuer une analyse non invasive d'attributs physiologiques, tels que le rythme cardiaque, la pression sanguine, le débit cardiaque, la réponse respiratoire ou la composition corporelle et d'analytes de la chimie sanguine tels que le glucose, le lactate, l'hémoglobine et la saturation en oxygène. Le fait d'utiliser une combinaison de capteurs différents à fonctions multiples, tels que des capteurs optiques et électriques, permet d'améliorer les dispositifs et les techniques de mesure physiologique connus. La configuration particulière d'un ou plusieurs capteurs à fonctions multiples permet de mesurer de manière non invasive des données optiques à longueurs d'ondes multiples ainsi que des données d'électrocardiogramme et/ou d'impédance bioélectrique et/ou des données spectroscopiques d'impédance RF. Ces informations sont utilisées pour développer un algorithme non linéaire autoconsistant afin de dériver les attributs physiologiques tout en compensant diverses formes d'effets perturbateurs tes que des artefacts dus aux mouvements, la variabilité de la fixation des capteurs, la variabilité des composants du dispositif, la variabilité physique et physiologique du sujet et divers attributs physiologiques perturbateurs.

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