Non-invasive method for collecting biological data for...

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G01N 33/68 (2006.01)

Patent

CA 2704613

The invention relates to a non-invasive method for collecting biological data that can be used for establishing a diagnosis of or a prognosis for a particular skin pathology in a patient, characterized in that: a) a skin sample containing biological material is taken by applying a layer of adhesive to the skin of said patient, and then by removing said adhesive, b) at least one protein of which the presence, the absence, or the variation in amount or in concentration relative to a standard value is associated with the presence of, with a change in or with the absence of a particular skin pathology, is detected by mass spectrometry in said sample. Such a method is particularly suitable for establishing a diagnosis of or a prognosis for psoriasis.

L'invention se rapporte à une méthode non-invasive de recueil de données biologiques utiles pour l'établissement d'un diagnostic ou d'un pronostic d'une pathologie cutanée particulière chez un patient, caractérisée en ce que: a) on prélève un échantillon cutané contenant du matériel biologique, par application sur la peau dudit patient d'une couche d'adhésif, puis par retrait dudit adhésif, b) on détecte par spectrométrie de masse dans ledit échantillon au moins une protéine dont la présence, l'absence, ou la variation de quantité ou de concentration par rapport à une valeur standard est associée à la présence, à l'évolution ou à l'absence d'une pathologie cutanée particulière. Une telle méthode est particulièrement adaptée pour l'établissement d'un diagnostic ou d'un pronostic du psoriasis.

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