Non-invasive non-spectrophotometric infrared measurement of...

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G01N 21/31 (2006.01) A61B 5/00 (2006.01) G01N 21/35 (2006.01) G01N 21/47 (2006.01)

Patent

CA 2180128

A new non-invasive non-spectrophotometric method for measuring the blood concentration of ana- lytes such as glucose has been developed. A plurality of broad spectrum filters (30A-30D) transmit distin- guishably coded by choppers (20A-20D) beams of radiation in overlapping portions of the spectrum to the sample. Radiation reflected or transmitted by the sample is detected and decoded. LED's may be used instead of the broad spectrum radiation generating device and the filters. Further, a scanning interfer- ometer cam be used as the illuminating and coding device. In a preferred mode, congruent illumination is utilized. The coded signals are analyzed by anal- ogy to colorimetry and visual processing and can be converted into concentration measurements.

L'invention concerne un nouveau procédé de mesure non spectrophotométrique non invasive de concentrations dans le sang de substances telles que le glucose. Plusieurs filtres (30A-30D) à large spectre transmettent à l'échantillon prélevé des faisceaux de rayons codés de manière différenciée par des découpeurs (20A-20D), dans les zones du spectre qui se chevauchent. Les rayons réfléchis ou émis par l'échantillon sont détectés et décodés. Des DEL peuvent être utilisées à la place des filtres et du système de production de faisceaux de rayons à large spectre. De plus, un interféromètre d'exploration peut faire office de système d'éclairement et de codage. Dans un mode préféré de réalisation, on fait appel à l'éclairement congruent. Les signaux codés sont analysés par analogie en vue de la colorimétrie et du traitement visuel et peuvent être convertis en mesure de concentration.

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