Non-invasive prenatal genetic diagnosis using transcervical...

Details Non-invasive prenatal genetic diagnosis using transcervical... Non-invasive prenatal genetic diagnosis using transcervical...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2521032

A non-invasive, risk-free method of prenatal diagnosis is provided. According to the method of the present invention transcervical specimens are subjected to trophoblast-specific immunostaining followed by FISH and/or PRINS analyses in order to determine fetal gender and/or identify chromosomal abnormalities in a fetus.

La présente invention se rapporte à un procédé sans risque et non invasif de diagnostic prénatal. Conformément au procédé de la présente invention, des échantillons de cellules transcervicales sont soumises à une coloration immunologique spécifique des trophoblastes, puis à des analyses FISH et/ou PRINS, aux fins de la détermination du sexe du foetus et/ou de l'identification d'anomalies chromosomiques dans un foetus.

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