A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/60 (2006.01) A61K 8/368 (2006.01) A61K 8/55 (2006.01) A61Q 17/00 (2006.01) A61Q 19/00 (2006.01)
Patent
CA 2278010
The invention provides methods and compositions which are mild and nonirritating for reducing and eliminating skin disorders, particularly blemishes and redness associated with acne. The hydroalcoholic compositions of the invention contain a keratolytic compound, preferably a .beta.-hydroxy carboxylic acid, more preferably salicylic acid or pharmaceutically acceptable salt thereof; and a phosphate ester or salt of a nonsaccharide C2-C18 polyhydric alcohol or a mono- or disaccharide polyol, formulated with pharmaceutically acceptable carriers. Preferred glycerophosphate salts for use in the methods and compositions of the invention are sodium glycerophosphate and calcium glycerophosphate. Additional anti-irritancy agents are not required in the compositions of the present invention, as the glycerophosphate salt component uniquely endows the compositions with nonirritant properties. Other components which may be formulated into the compositions of the invention include fragrances, colorants, emollients, humectants and antimicrobial agents.
L'invention porte sur des procédés et des compositions douces et non irritantes permettant de réduire et d'éliminer les états dermatologiques, notamment les lésions et les rougeurs associées à l'acné. Les compositions aqueuses à base d'alcool contiennent un composé kératolytique, de préférence un acide .beta.-hydroxy carboxylique, plus souhaitablement un acide salicylique ou un sel pharmaceutiquement acceptable de celui-ci; et un ester ou sel de phosphate d'un polyol en C¿2?-C¿18? non saccharide ou un polyol mono- ou disaccharide formulé avec des supports pharmaceutiquement acceptables. Des sels de glycérophosphate préférés destinés à être utilisés dans les procédés et les compositions de l'invention sont le glycérophosphate de sodium et le glycérophosphate de calcium. Il n'est pas nécessaire d'ajouter des agents anti-irritants dans les compositions de l'invention, le sel de glycérophosphate seul conférant aux compositions des propriétés non irritantes. D'autres composants pouvant être formulés dans les compositions de l'invention sont des parfums, des colorants, des émollients, des humectants et des agents anti-microbiens.
Mayes-Smith Joyce
O'halloran David P.
Rudtke Deborah
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
Non-irritating composition for treating acne and other skin... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Non-irritating composition for treating acne and other skin..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-irritating composition for treating acne and other skin... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1675449