A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/67 (2006.01) A61K 8/11 (2006.01) A61K 8/55 (2006.01) A61K 8/60 (2006.01) A61K 8/64 (2006.01) A61Q 19/00 (2006.01)
Patent
CA 2273026
The present invention relates to a cosmetic or pharmaceutical emulsion for topical application to the skin comprising an irritating agent and at least one non-disruptive emulsifier. In a preferred embodiment the irritating agent is a retinoid. The invention also provides a method for decreasing the irritation on the skin caused by an irritating active agent in a topical cosmetic or pharmaceutical emulsion which comprises employing as an emulsifier at least one of an alkyl polyoside, a grafted water soluble protein on a hydrophobic backbone, and lecithin.
La présente invention concerne une émulsion cosmétique ou pharmaceutique destinée à être appliquée de façon topique sur la peau. Ladite émulsion comprend un agent irritant et au moins un émulsifiant adoucissant. Selon un mode de réalisation préféré, l'agent irritant est un rétinoïde. L'invention concerne également un procédé permettant de réduire l'irritation de la peau provoquée par un agent actif irritant d'une émulsion pharmaceutique ou cosmétique topique, lequel procédé consiste à utiliser comme émulsifiant au moins un polyoside d'alkyle, un protéine soluble dans l'eau greffée sur un squelette hydrophobe, et de la lécithine.
Castillo-Bucci Carmen
Knight E. Althea
Maes Daniel H.
Zecchino Jules
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
E-L Management Corp.
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