Non-nucleoside anti-hepacivirus agents and uses thereof

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 275/24 (2006.01) A61K 31/15 (2006.01) A61K 31/197 (2006.01) A61K 31/198 (2006.01) C07C 237/22 (2006.01) C07C 271/22 (2006.01) C07C 275/28 (2006.01) C07C 275/34 (2006.01) C07D 209/08 (2006.01) C07D 213/75 (2006.01) C07D 233/54 (2006.01) C07D 295/20 (2006.01) C07D 307/68 (2006.01) C07D 333/24 (2006.01)

Patent

CA 2613354

The present disclosure provides amide-based, non-nucleoside compounds having antiviral activity against Hepacivirus, such as hepatitis C virus (HCV) , methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of viral infections. The present disclosure also provides methods for identifying amide-based, non-nucleoside compounds having antiviral activity.

L'invention concerne des composés non-nucléosides à base d'amide possédant une activité antivirale contre l'hépacivirus, telle que le virus de l'hépatite (HCV), des procédés et des intermédiaires destinés à synthétiser ces composés, ainsi que des procédés d'utilisation de ces composés dans divers contextes, notamment le traitement et la prévention d'infections virales. L'invention concerne également des procédés destinés à identifier les composés non nucléosides, à base d'amide possédant une activité antivirale.

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