Non-nucleoside reverse transcriptase inhibitors

Details Non-nucleoside reverse transcriptase inhibitors Non-nucleoside reverse transcriptase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 233/72 (2006.01) A61K 31/4174 (2006.01) A61K 31/513 (2006.01) A61P 31/18 (2006.01) C07D 233/78 (2006.01) C07D 239/22 (2006.01) C07D 239/54 (2006.01) C07D 239/545 (2006.01) C07D 239/553 (2006.01)

Patent

CA 2687747

Compounds of formula (I), wherein R1, X1, X2 and A, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula (I) useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.

La présente invention concerne des composés de formule (I), dans laquelle R1, X1, X2 et A sont tels que définis dans ce document, ou leurs sels acceptables sur le plan pharmaceutique, qui inhibent la transcriptase inverse du VIH-1 et procurent un procédé de prévention et de traitement d'infections par le VIH-1 et de traitement du SIDA et/ou du syndrome apparenté au SIDA (ARC). La présente invention concerne également des compositions contenant des composés de formule (I) utiles pour la prévention et le traitement d'infections par le VIH-1 et le traitement du SIDA et/ou du syndrome apparenté au SIDA (ARC).

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