Non-nucleoside reverse transcriptase inhibitors

Details Non-nucleoside reverse transcriptase inhibitors Non-nucleoside reverse transcriptase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61K 31/4162 (2006.01) A61P 31/18 (2006.01) C07D 231/56 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2658984

The present invention provides for compounds useful for treating an HIV infection, or preventing an HIV infection, or treating AIDS or ARC. The compounds of the invention are of formula I wherein A is A1, A2, A3 or A4 and R1, R2, R3, R4a, R4b, R5, R6, Ar, X1, X2, X3, X4 and X5 are as herein defined. Also disclosed in the present invention are methods of treating an HIV infection with compounds defined herein and pharmaceutical compositions containing said compounds.

La présente invention concerne des composés utiles pour traiter une infection à VIH, ou pour prévenir une infection à VIH, ou pour traiter le SIDA ou l'ARC. Les composés de l'invention sont de formule I, dans laquelle A est A1, A2, A3 ou A4 et R1, R2, R3, R4a, R4b, R5, R6, Ar, X1, X2, X3, X4 et X5 sont comme définis par le présent document. La présente invention concerne également des procédés destinés à traiter une infection à VIH avec des composés définis dans le présent document et des compositions pharmaceutiques contenant lesdits composés.

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