Non-nucleosidic coumarin derivatives as...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/00 (2006.01) C07D 311/16 (2006.01) C07D 407/12 (2006.01) C07D 491/052 (2006.01) C07D 493/04 (2006.01) C07F 9/547 (2006.01) C07F 9/655 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2159356

Phoroactivatable novel coumarin derivatives comprising a courmarin moiety linked to a non-nucleosidic backbone moiety are disclosed. The resulting molecules are typically used as photo cross-linking groups when incorporated into polynucleotides as replacements for one or more of the complementary nucleoside bases present in probes used in procedures involving nucleic acid hybridization reactions.

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