Non-pancreatic proteases for controlling plasma...

Details Non-pancreatic proteases for controlling plasma... Non-pancreatic proteases for controlling plasma...

A - Human Necessities

61

K

A61K 38/48 (2006.01)

Patent

CA 2544156

This invention relates to methods for maintaining the basal level or reducing the level of cholecystokinin (CCK) in blood plasma of a mammal. Additionally, the invention provides methods for treating pain in a mammal and more particularly, methods for treating abdominal pain in a mammal. The methods include administering to the mammal a non-pancreatic protease or a composition comprising a non-pancreatic protease. The methods of this invention are particularly useful for treating abdominal pain in a mammal suffering from acute or chronic pancreatitis and related conditions.

L'invention concerne des procédés destinés à maintenir le niveau de basal ou à réduire le niveau de cholécystokinine (CCK) dans le plasma sanguin d'un mammifère. En outre, l'invention concerne des procédés destinés à traiter la douleur chez un mammifère et plus particulièrement, des procédés de traitement de la douleur abdominale chez un mammifère. Les procédés de l'invention consistent à administrer au mammifère une protéase non pancréatique ou une composition contenant une telle protéase. Ces procédés sont particulièrement utiles dans le traitement de douleurs abdominales chez un mammifère souffrant de pancréatite chronique ou aiguë ainsi que des états connexes.

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