C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) A61K 35/76 (2006.01) A61K 39/21 (2006.01) C12N 7/04 (2006.01) C12N 15/49 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2183154
The present invention relates to non-pathogenic strains of HIV-1 and to components parts, fragments and derivatives thereof and to genetic sequences derived therefrom and their use in the development of diagnostic and therapeutic compositions for the treatment and prophylaxis of AIDS and AIDS-related disorders. The present invention also relates to a method for attenuating pathogenic strains of HIV-1 by mutagenizing particular regions of the HIV-1 genome.
La présente invention a pour objet des souches non pathogènes de VIH-1 et des composants, parties, fragments et dérivés de ceux-ci ainsi que des séquences génétiques tirées de ceux-ci et leur utilisation dans l'élaboration de compositions à usage diagnostique et thérapeutique pour le traitement et la prévention du SIDA et des troubles liés au SIDA. L'invention se rapporte également à un procédé pour l'atténuation des souches pathogènes de VIH-1 par mutagénisation de certaines régions du génome du VIH-1.
Cooper David
Crowe Suzanne
Deacon Nicholas John
Learmont Jennifer Catherine
Mcphee Dale Alan
Australian Red Cross Society
Fetherstonhaugh & Co.
The Macfarlane Burnet Centre For Medical Research Limited
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