Non-peptide bradykinin antagonists and pharmaceutical...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 405/12 (2006.01) A61K 31/496 (2006.01) C07D 215/26 (2006.01)

Patent

CA 2583920

Non-peptide compounds having activity as selective antagonists of bradykinin (BK) B2 receptor. The compounds are chemically characterized by the presence of an amino acid alpha substituted with a cyclic group and by a tetraalkylammonium group.

La présente invention concerne des composés non peptidiques possédant une activité d'antagonistes sélectifs des récepteur B2 de bradykinine (BK). Ces composés sont chimiquement caractérisés par la présence d'un acide aminé alpha substitué avec un groupe cyclique et par un groupe tétraalkylammonium 6.

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