A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/06 (2006.01) A61K 31/495 (2006.01) A61K 38/13 (2006.01) A61K 38/17 (2006.01) A61P 37/06 (2006.01)
Patent
CA 2417636
This invention is directed to pharmaceutical compositions useful in treating heart transplant rejection in mammals comprising a pharmaceutically acceptable excipient, a therapeutically effective amount of a non-peptide CCR1 receptor antagonist and a sub-nephrotoxic amount of cyclosporin A.
L'invention concerne des compositions pharmaceutiques utiles pour combattre une réaction de rejet consécutive à une transplantation cardiaque chez des mammifères. Ces compositions comprennent un excipient pharmaceutiquement acceptable, une dose thérapeutiquement efficace d'un antagoniste non peptidique du récepteur CCR1 ainsi qu'une dose sous-néphrotoxique de cyclosporine A.
Marks & Clerk
Schering Aktiengesellschaft
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