C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01)
Patent
CA 2255731
Invented are non-peptide G-CSF mimetics. Also invented are substitued 2,5- Diimino-3a,6a-diaryl-1,2,3,3a,4,5,6,6a-octahydroimidazo[4,5-d]imidazoles, pharmaceutical compositions containing these compounds, and methods of using these compounds as G-CSF mimetics. Also invented are novel processes used in preparing these compounds.
L'invention concerne des composés mimétiques du G-CSF non peptidiques. L'invention décrit également des 2,5-diimino-3a,6a-diaryl-1,2,3,3a,4,5,6,6a-octahydroimidazo[4,5-d]imidazoles substitués, des compositions pharmaceutiques contenant ces composés et des procédés d'utilisation desdits composés comme composés mimétiques du G-CSF. L'invention concerne en outre de nouveaux procédés utilisés dans la préparaiton desdits composés.
Breen Ann L.
Chan James A.
Luengo Juan I.
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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