Non-peptide peptidomimetics

Details Non-peptide peptidomimetics Non-peptide peptidomimetics

C - Chemistry, Metallurgy

07

H

C07H 15/18 (2006.01) A61K 31/70 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2175195

Compounds are provided which are crossreactive with peptides such as those which bind G-protein-linked receptors, together with preparative and therapeutic methods therefor. The compounds have general structure (3), wherein at least one of R1, R2, R3, R4 or R5 comprises a functional group which is chemically similar to that found in the peptide of interest.

L'invention concerne des composés pouvant participer à une réaction croisée avec des peptides, tels que ceux qui se fixent à des récepteurs liés avec la protéine G, ainsi que des procédés thérapeutiques et des procédés de préparation correspondants. Lesdits composés présentent la structure (3), dans laquelle au moins un groupe parmi R¿1?, R¿2?, R¿3?, R¿4? ou R¿5? comprend un groupe fonctionnel chimiquement similaire à celui qu'on trouve dans le peptide concerné.

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