Non-peptide renin inhibitors

Details Non-peptide renin inhibitors Non-peptide renin inhibitors

C - Chemistry, Metallurgy

07

D

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C07D 211/46 (2006.01) C07C 237/08 (2006.01) C07C 317/28 (2006.01) C07C 323/58 (2006.01) C07D 203/18 (2006.01) C07D 211/44 (2006.01) C07D 211/62 (2006.01) C07D 211/96 (2006.01) C07D 233/54 (2006.01) C07D 295/185 (2006.01) C07D 401/12 (2006.01) C07D 407/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 1337909

A renin inhibiting compound of the formula: Image wherein A is a substituent; R1 is hydrogen, loweralkyl, substituted loweralkyl or loweralkenyl; X is CH2, CHOH, C(O), O, S, S(O), SO2, NH, N(O) or -P(O)O-; R3 is loweralkyl, loweralkenyl or substituted loweralkyl; and T is mimic of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof.

615201

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