Non-peptide tachykinin receptor antagonists

Details Non-peptide tachykinin receptor antagonists Non-peptide tachykinin receptor antagonists

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 209/12 (2006.01) C07D 307/80 (2006.01)

Patent

CA 2176130

This invention provides a series of substituted benzofurans and indoles useful as non-peptide tachykinin receptor antagonists. This invention also provides methods for treating or preventing conditions associated with an excess of tachykinins which methods comprise administration of one or more of the compounds of the instant invention as well as formulations employing the compounds of this invention.

La présente invention décrit une série de benzofurannes et d'indoles substitués utiles comme antagonistes non peptidiques des récepteurs des tachykinines. Elle décrit également des procédés pour traiter ou prévenir des états pathologiques associés à un excès de tachykinines. Ces procédés consistent à administrer un ou plusieurs des composés décrits ainsi que des formulations les mettant en oeuvre.

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