Non-peptidyl inhibitors of vla-4 dependent cell binding...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 413/04 (2006.01) A61K 31/421 (2006.01) A61P 37/00 (2006.01) C07C 229/34 (2006.01) C07C 233/47 (2006.01) C07C 311/06 (2006.01) C07D 235/14 (2006.01) C07D 261/08 (2006.01) C07D 263/32 (2006.01) C07D 403/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2396087

There is disclosed a genus of non-peptidyl compounds, wherein said compounds are VLA-4 inhibitors useful in treating inflammatory, autoimmune, and respiratory diseases, and wherein said compounds comprise a compound of formula (1Ø0) and pharmaceutically acceptable salts and other prodrug derivatives thereof.

L'invention concerne un type de composés non peptidyle qui sont des inhibiteurs de VLA-4 et sont utiles pour traiter des maladies inflammatoires, auto-immunes et respiratoires, lesdits composés comprenant un composé représenté par la formule (1Ø0) : (1Ø0), ainsi que leurs sels et autres dérivés ou promédicaments acceptables sur le plan pharmaceutique.

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