Non-receptor mediated imaging agents

Details Non-receptor mediated imaging agents Non-receptor mediated imaging agents

C - Chemistry, Metallurgy

07

K

C07K 14/46 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2231352

Detectably labelled non-receptor mediated cell-associating compounds are provided for use in the diagnostic imaging of target sites in a mammal. Cell- associating compounds may be directly labelled, or labelled via a chelating compound to form a conjugate. Such cell-associating compounds are particularly useful to image target sites such as tumour sites and sites of infection.

L'invention concerne des composés s'associant à des cellules, à médiation non liée aux récepteurs, marqués de manière à pouvoir être détectés, qui conviennent pour la visualisation diagnostique de récepteurs cibles chez un mammifère. Ces composés peuvent être marqués directement, ou bien marqués au moyen d'un composé chélateur de façon à former un conjugué. Ils sont particulièrement intéressants pour visualiser des récepteurs cibles tels que des tumeurs et des infections.

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