Non-steroidal anti-inflammatory drugs for the...

A - Human Necessities – 61 – K

Patent

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A61K 31/60 (2006.01) A61K 31/135 (2006.01) A61K 31/167 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/196 (2006.01) A61K 31/355 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/545 (2006.01)

Patent

CA 2222929

The invention concerns the recognition that certain non-steroidal anti- inflammatory agents produce cytoprotective effects on trabecular cells, and thus can be used to prevent injury of the cells and treat the loss of trabecular cells caused by oxidative or other forms of injury to the cells. Such treatment can ameliorate the severity or prevent glaucoma.

Cette invention concerne la capacité de certains agents non stéroïdiens et anti-inflammatoires à produire des effets cytoprotecteurs sur des cellules trabéculaires. Ces médicaments peuvent être employés afin de prévenir des lésions des cellules, et de traiter la perte de cellules trabéculaires engendrée par des lésions de type oxydante ou autre de ces cellules. Un tel traitement permet de limiter la gravité des glaucomes ou de les prévenir.

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