Non-steroidal ligands for the estrogen receptor

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 233/11 (2006.01) A61K 31/135 (2006.01) A61K 31/165 (2006.01) C07C 33/28 (2006.01) C07C 45/45 (2006.01) C07C 45/59 (2006.01) C07C 47/548 (2006.01) C07C 49/796 (2006.01) C07C 57/42 (2006.01) C07C 69/618 (2006.01) C07C 211/28 (2006.01) C07C 233/22 (2006.01) C07C 233/40 (2006.01) C07C 233/58 (2006.01) C07C 251/40 (2006.01) C07C 255/07 (2006.01) C07C 255/34 (2006.01) C07C 327/44 (2006.01) C07D 271/06 (2006.01) C07D 295/185 (2006.01) C07F 9/40 (2006.01)

Patent

CA 2301189

Novel non-steroidal ligands for the estrogen receptor which possess tissue- dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating a variety of disease states.

La présente invention concerne des ligands non stéroïdiens pour le récepteur oestrogénique. Ces ligands présentent une activité oestrogénique liée au tissus ainsi qu'une activité anti-oestrogénique. L'invention concerne également des procédés d'élaboration de ces ligands. L'invention concerne enfin l'application de ces ligands pour traiter divers états pathologiques.

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