Nonthrombogenic implant surfaces

Details Nonthrombogenic implant surfaces Nonthrombogenic implant surfaces

C - Chemistry, Metallurgy

08

F

C08F 293/00 (2006.01) A61L 33/00 (2006.01) A61L 33/08 (2006.01) C08B 37/00 (2006.01) C08B 37/02 (2006.01)

Patent

CA 2154166

Triblock polymers comprised of polysaccharide, such as heparin or dextran, and a hydrocarbon chain, have been pre- pared. The triblock polymer adsorbs strongly on the surface of hydrophobic polymer substrates such as polyethylene, through hy- drophobic interaction between the polymer and the hydrophobic hydrocarbon chain of the triblock polymer. The surface ad- sorbed with triblock polymer is resistant to protein deposition, which renders the surface nonthrombogenic.

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