Normalization of complex analyte mixtures

Details Normalization of complex analyte mixtures Normalization of complex analyte mixtures

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2616552

The present invention relates to methods and compositions for the normalization of complex analyte mixtures. The invention allows the preparation of profiled samples from highly complex analyte mixtures, allowing the identification of relevant targets or biomarkers. The invention also relates to methods for producing devices, such as a support, suitable for normalization of complex analyte samples. The invention can be used for the normalization of any complex mixture, such as immunogenic libraries, particularly of human source, and to identify or produce biomarkers highly relevant to human traits or conditions.

L'invention concerne des méthodes et des compositions de normalisation de mélanges d'analytes complexes. L'invention permet la préparation d'échantillons profilés de mélanges d'analytes hautement complexes, permettant l'identification de cibles ou de biomarqueurs d'intérêt. L'invention concerne également des procédés de production de dispositifs, par exemple un support, adaptés pour la normalisation d'échantillons d'analytes complexes. L'invention peut être utilisée pour normaliser n'importe quel mélange complexe, par exemple des banques immunogéniques, en particulier de source humaine, et pour identifier ou produire des biomarqueurs hautement significatifs par rapport aux traits ou états humains.

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