C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/06 (2006.01) A61K 31/496 (2006.01) C07D 241/04 (2006.01) C07D 295/084 (2006.01) C07D 307/52 (2006.01) C07D 333/20 (2006.01) C07D 407/02 (2006.01) C07D 407/04 (2006.01) C07D 409/02 (2006.01)
Patent
CA 2403139
Novel 1-[1-(hetero)aryl-1-perhydroxyalkylmethyl]--piperazine compounds which are antagonistic to tachykinin receptors, of the general formula I, (see formula I) wherein R6, R7, A and Z have the meanings given in the description, and medicaments containing these compounds are described. Furthermore, a process for the preparation of the novel compounds and intermediate products of this process are described.
Nouveaux composés à base de 1-¬1-(hétéro)aryl-1-perhydroxyalkylméthyl|-pipérazine présentant une activité antagoniste vis-à-vis des récepteurs à la tachykinine, représentés par la formule générale I (voir la formule I), où R6, R7, A et Z ont les significations définies dans la description, et médicaments contenant ces composés. Procédé permettant de préparer lesdits nouveaux composés et produits intermédiaires associés audit procédé.
Antel Jochen
Brueckner Reinhard
David Samuel
Eeckhout Christian
Jasserand Daniel
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Solvay Pharmaceuticals Gmbh
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