Novel 1,2-diphenylethene derivatives for treatment of immune...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 255/37 (2006.01) A61K 31/05 (2006.01) A61P 37/00 (2006.01) C07C 39/21 (2006.01) C07C 39/373 (2006.01) C07C 43/215 (2006.01) C07C 59/52 (2006.01) C07C 69/017 (2006.01) C07C 69/16 (2006.01) C07D 213/30 (2006.01) C07D 307/42 (2006.01) C07D 333/16 (2006.01)

Patent

CA 2433417

The invention provides novel 1,2-diphenylethene derivatives and pharmaceutically acceptable salts thereof, the process for production of these compounds and their pharmaceutical composition and the use of these compounds as modulators of T-cells, neutrophils, macrophages and their associated cytokines as agents for treating immune, inflammatory and auto-immune diseases.

L'invention concerne de nouveaux dérivés de 1,2-diphényléthène et leurs sels pharmaceutiquement acceptables, le procédé de production de ces composés et de leur composition pharmaceutique ainsi que l'utilisation de ces composés en tant que modulateurs de lymphocytes T, de neutrophiles, de macrophages et de leurs cytokines associées et en tant qu'agents servant à traiter des maladies immunes, inflammatoires et auto-immunes.

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