C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/87 (2006.01)
Patent
CA 2703783
Disclosed herein are novel 1,3-dihydro-5-isobenzofurancarbonitrile derivatives represented by Formula 1, or pharmaceutically acceptable salts thereof. Also disclosed is a pharmaceutical composition for treating or preventing premature ejaculation including the compound. The 1,3-dihydro-5-isobenzofurancarbonitrile derivatives have a short half- life and inhibit the ejaculation process by selectively inhibiting serotonin reuptake via a serotonin reuptake transporter present in a presynaptic neuron. Thus, the compounds are useful in the treatment and prevention of premature ejaculation.
Dérivés de l,3-dihydro-5-isobenzofurancarbonitrile, ou sels de ces dérivés de qualité pharmaceutique. L'invention concerne également une composition pharmaceutique incluant un tel composé et axée sur le traitement ou la prévention de l'éjaculation précoce. Les dérivés de l,3-dihydro-5-isobenzofurancarbonitrile ont une demi-vie brève et bloquent le processus de l'éjaculation par inhibition du recaptage de la sérotonine via un transporteur de recaptage de la sérotonine présent dans un neurone présynaptique. Ces composés sont donc utiles pour le traitement ou la prévention de l'éjaculation précoce.
Ahn Byoung-Ok
Ahn Gook-Jun
Choi Seul-Min
Choi Soo-Jung
Kang Kyung-Koo
Dong-A Pharmaceutical. Co. Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Novel 1,3-dihydro-5-isobenzofurancarbonitrile derivatives... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel 1,3-dihydro-5-isobenzofurancarbonitrile derivatives..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel 1,3-dihydro-5-isobenzofurancarbonitrile derivatives... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1901116