Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/52 (2006.01) A61K 31/403 (2006.01)

Patent

CA 2659215

The invention provides novel, multiply-substituted l-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.

La présente invention concerne de nouveaux 1-aryl-3-azabicyclo[3.1.0]hexanes polysubstitués, ainsi que les procédés et intermédiaires correspondants pour la synthèse de ces composés, de même que des préparations et des méthodes employant ces composés dans le traitement prophylactique et/ou thérapeutique de troubles du système nerveux central (SNC), y compris la dépression et l'anxiété.

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