C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A61K 31/7048 (2006.01)
Patent
CA 2525455
The present invention relates to 14- or 15-membered macrolides substituted at the 4" position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infections in a human or animal body.
La présente invention concerne des macrolides ramifiés en 14 ou en 15 substitués en position 4'', représentés par la formule (I) et des dérivés de ceux-ci répondant aux normes pharmaceutiques. Cette invention concerne aussi des processus de préparation de ces composés ainsi que l'utilisation de ceux-ci dans une thérapie ou une prophylaxie d'infections microbiennes systémiques ou topiques chez un homme ou un animal.
Alihodzic Sulejman
Berge John Michael
Lewis Jarvest Richard
Glaxo Group Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Pliva - Istrazivacki Institut D.o.o.
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