Novel 17-halogenated 19-nor steroids, method and...

C - Chemistry – Metallurgy – 07 – J

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C07J 41/00 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2336167

The invention concerns compounds of formula (I) wherein, in particular: X = halogen; Y = single bond, O, NH, S, SO or SO¿2?; Z = hydrogen or halogen; n, R¿1?, R¿2?, R¿3? and R¿4? are as defined in the description. The invention also concerns the method and intermediates for preparing said compounds, their use as medicines and pharmaceutical compositions containing them.

L'invention a pour objet les composés de formule (I): dans laquelle notamment X = halogène; Y = simple liaison, O, NH, S, SO ou SO2; Z = hydrogène ou halogène; n, R1, R2, R3 et R4 sont tels que définis dans la description, leurs procédé et intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.

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